| 2025-06-11 19:30:0011/06/2025 | Noordwijk — Kozakken Boys | 1 - 0Full Time |
| 2025-06-11 20:00:0511/06/2025 | Almkerk — Mierlo Hout | 0 - 5Full Time |
| 2025-06-14 16:00:0014/06/2025 | Kozakken Boys — Noordwijk | 4 - 0Full Time |
| 2025-06-14 17:00:0014/06/2025 | MZC’11 — DAW | 1 - 4Full Time |
| 2025-06-14 17:00:0014/06/2025 | Nivo Sparta — Gilze | 3 - 4Full Time |
| 2025-06-15 14:30:0015/06/2025 | Gastel — Dommelen | 3 - 1Full Time |
| 2025-06-15 14:30:0015/06/2025 | GSBW — Haarsteeg | 2 - 1Full Time |
| 2025-06-15 14:30:0015/06/2025 | Bekkerveld — ALFA Sport (Na verlenging) | 4 - 2Full Time |
| 2025-06-15 14:30:0015/06/2025 | Sparta’18 — RKHSV | 4 - 1Full Time |
| 2025-06-15 14:30:0015/06/2025 | Prinses Irene — Sporting Heerlen | 1 - 2Full Time |
| 2025-06-15 14:30:0015/06/2025 | HVV Helmond — Olympia'18 (Na verlenging) | 2 - 0Full Time |
| 2025-06-15 14:30:0015/06/2025 | Braakhuizen — Juliana Mill (Na verlenging) | 4 - 3Full Time |
| 2025-06-15 14:30:0015/06/2025 | Eli — Nooit Gedacht | 0 - 2Full Time |
| 2025-06-15 14:30:0015/06/2025 | DVG — Meterik | 3 - 0Full Time |
| 2025-06-15 14:30:0015/06/2025 | Keer — UOW'02 | 0 - 3Full Time |
| 2025-06-15 14:30:0015/06/2025 | Lindenheuvel HB* (wns) — FC Roerdalen | 1 - 1Full Time |
| 2025-06-15 14:30:0015/06/2025 | FC Uden — DSV | 2 - 1Full Time |
| 2025-06-15 14:30:0015/06/2025 | RKUVC — Excellent | 4 - 0Full Time |
| 2025-06-15 14:30:0015/06/2025 | Nieuw Woensel — DOSL | 1 - 2Full Time |
| 2025-06-15 14:30:0015/06/2025 | RKVV Keldonk* (wns) — Zwentibold | 1 - 1Full Time |
| 2025-06-15 14:30:0015/06/2025 | VV Hellas — De Zwaluw | 0 - 3Full Time |
| 2025-06-15 14:30:0015/06/2025 | BVV’27 — Sambeek (Na verlenging) | 1 - 0Full Time |
| 2025-06-15 14:30:0015/06/2025 | VV Linne — SVME | 4 - 3Full Time |
| 2025-06-15 14:30:0015/06/2025 | DESM — Woander Forest | 0 - 1Full Time |
| 2025-06-15 14:30:0015/06/2025 | DWSH’18 — FC Ria | 1 - 0Full Time |
| 2025-06-15 14:30:0015/06/2025 | FC Bemelen — SSE | 1 - 3Full Time |
| 2025-06-15 14:30:0015/06/2025 | Slekker Boys — Hapse Boys | 1 - 2Full Time |